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Description
Side effects that feel unmanageable in the first few weeks may be very manageable with dietary adjustments, OTC medications, and a modified dose escalation schedule

Oral semaglutide, by contrast, has poor oral bioavailability and would require a much higher maternal dose to achieve therapeutic levelsbut even then, peptide digestion would prevent any active compound from reaching an infant's bloodstream

Have Leber's hereditary optic neuropathy (B12 contraindicated)

1A) and GIPR expression is very low (Supplementary Fig
