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It was reported that the weight loss property (5-10%) of GLP-1 analogs is hampered by dose-dependent side-effects 10

If you notice that a hard lump remains or if the injection site becomes red, swollen, or painful, contact your healthcare provider as soon as possible

To date, the presence of GLP-1R in the renal vasculature has been confirmed but not in the tubules ( Oxidative Stress/Inflammation GLP-1RAs have been shown to prevent renal oxidative stress by inhibiting nicotinamide adenine dinucleotide phosphate (NADPH) oxidase through the activation of PKA and the production of cyclic adenosine monophosphate (cAMP)

Your provider will guide you on a treatment regimen that may include an increase in dose every four weeks