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This shift happens because tirzepatide activates GIP and GLP-1 receptors that slow gastric emptying and enhance satiety signals

In these studies, researchers find out important information about the drug, such as adverse effects, other safety considerations, and how well the drug works

[DOI] [PMC free article] [PubMed] [Google Scholar] 62.Gastaldelli A, Cusi K, Fernndez Land L, Bray R, Brouwers B, Rodrguez

It is approved in several countries, including the USA, as an adjunct to diet and exercise for the treatment of adults with T2D and in combination with a reduced-calorie diet and increased physical activity to reduce excess bodyweight and maintain weight reduction long-term in adults with obesity or overweight with at least one weight-related comorbid condition [8,9,10]