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In the SURMOUNT clinical trials, participants using the highest dose (15 mg) achieved an average weight loss of approximately 1520% of their initial body weight over 72 weeks when combined with intensive lifestyle support
However, circulating GLP-1 was found to be positively associated with total coronary load in humans in a fully adjusted model [OR: 2.53 (95% CI: 1.12-6.08
Changes in albuminuria predict cardiovascular and renal outcomes in type 2 diabetes: a post hoc analysis of the LEADER Trial
