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Existing evidence doesnt suggest tirzepatide poses a risk of birth defects after early inadvertent exposure, but thats a different statement from saying its safe to use during pregnancy

Researchers are still learning about their other potential uses

It is being studied for obesity, T2D, MASLD, obstructive sleep apnea, and knee osteoarthritis linked to obesity.[4] Eli Lilly began developing retatrutide after the early commercial success of tirzepatide (the dual-agonist molecule that became Mounjaro and Zepbound) signaled that adding more hormone-receptor targets to a single molecule could push weight loss meaningfully higher than what a GLP-1 drug alone could deliver

Yes, tirzepatide can be safely combined with most other diabetes medications, including metformin, SGLT2 inhibitors, and insulin