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Taking the tablet whole also ensures proper absorption thanks to the drug's bioavailability, or the extent to which an active ingredient is absorbed, enters the bloodstream, and reaches the site of action in the body to produce an effect

Understanding these fundamental effects on digestion helps contextualize why some patients and practitioners consider supplemental digestive enzymes during treatment, though the evidence base for this practice requires careful examination

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This exclusion has been in place since the Part D prescription drug benefit launched in 2006