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Moreover, while starting an anti-obesity medical treatment, the clinicians should pay particular attention to possible concomitant obesogenic prescription medications, including all drugs in the classes of glucocorticoids, -blockers, antihistamines, as well as selected agents in the classes of antidepressants, antipsychotics, antidiabetics, and contraceptives that are progestin-only [18]

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To further elucidate which GLP-1R-expressing cells are involved in the abovementioned cardio- and vasoprotective benefits, liraglutide was administered to wild-type (C57BL/6J), global Glp1r knockout ( Glp1r / ), endothelial cell- ( Cdh5 Cre ) and myeloid cell ( LysM Cre )-specific knockout of Glp1r and arterial hypertension was induced by angiotensin II

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