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Description
Our study confirmed that the PI3K/Akt pathway acts downstream of GLP-1R in the TNC in CM mice

Rubbing the injection site gently with a warm cloth for 10 to 15 seconds increases blood flow and may desensitize the area slightly, making needle insertion less noticeable

However, -arrestin-1 knockdown did not affect GLP-1 R surface expression and ligand-induced GLP-1 R internalization/desensitization

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