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Second, as compared with AHS animals, the circulating levels of chemokines (i.e., SDF-1 and GLP-1) and EPCs (i.e., C-kit/CD31+, Sca-1/CD31+, KDR/CD34+ and VE-Cadherin/CD34+) were remarkably increased in DPP4 D and Sita-treated animals, suggesting these results were mainly due to the suppression of DPP4 enzyme activity

doi: 10.1007/s00125-017-4303-6

In contrast, metabolic disorders and disorders related to dysfunctions in reward processing (i.e., major depressive disorder and substance use disorders) have received less attention to date

We integrate medical management with nutritional counseling and behavioral support