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Description
This dual synthetic polypeptide, glucose-dependent insulinotropic polypeptide (GIP), and glucagon-like peptide-1 ...
Tongue pain, dryness, or white patches
Here, we expressed the human GPR17 long isoform (hGPR17L) in GLUTag cells, a murine EEC line, and we used the GPR17 synthetic agonist MDL29,951 together with pharmacological probes and genetic approaches to quantitatively assess the contribution of GPR17 signaling to GLP-1 secretion
In addition, activating GLP-1R protected mitochondria against the TGF-1+IL-1-induced increase in oxidative phosphorylation in fibroblasts
