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In MetS, events such as increased oxidative stress and inflammatory cytokines generated by hyperglycemia and obesity can cause vascular endothelial dysfunction, compromising the vasomotor balance and increasing the adhesion of leukocytes to the endothelium in various organs and tissues, including the central nervous system (CNS) [79]

You may see it happen in 2026-27

The guide on switching from tirzepatide to semaglutide covers the logistics and expectations

In the United States, the Food and Drug Administration warned about selling unapproved semaglutide
