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Gerstein HC, Colhoun HM, Dagenais GR, et al

The EM structure of Tirzepatide bound to the complete GIPR and G-proteins (Figure 3, PDB ID 7rbt, Sun et al., 2022) shows some hydrophobic and some specific polar interactions between the peptidic drug and the GIP receptor molecule
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Koh A, De Vadder F, Kovatcheva-Datchary P, Bckhed F
