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N Engl J Med 2018;379:62332

What's more, a study in the journal Molecular Psychiatry reveals GLP-1 sends hunger-taming signals to the hypothalamus , the brain region that's been dubbed the "master regulator" of satiety

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Tirzepatide causes gastrointestinal side effects somewhat more frequently than semaglutide, likely due to its dual GLP-1/GIP action versus semaglutides single GLP-1 action
