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A mentionable possible confounder is weight loss in semaglutide arm was -9.39% (vs placebo -0.88%)
These hormones regulate blood glucose levels and appetite by enhancing insulin secretion, suppressing glucagon release, and slowing gastric emptying

Topiramate is approved by the FDA for treating partial-onset seizures and primary generalized tonic-clonic seizures in individuals 2 years and older, as well as for use with other medications to treat these and Lennox-Gastaut syndrome-related seizures

It is important to inform your doctor about all the medicines you currently take to ensure safe and effective treatment
