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Some patients may benefit from slower titration or temporary dose reduction if side effects are problematic
However, he said, he would be very hesitant to prescribe them himself
21 Remarkably, even in HF-free patients with morbid obesity, cardiac abnormalities can be seen that are consistent with left ventricular (LV) remodelling and dysfunction, including greater LV mass, LV diastolic dysfunction and elevated LV filling pressure
Frontiers in Endocrinology, 9, Article 576
