glp 1 analog drugs GLP-1 receptor agonists IUPHAR review – Glucagon-like peptide-1

Mimic natural GLP-1 hormone better glucose control Slow gastric emptying increased satiety Promote significant weight loss Reduce cardiovascular risks in many patients Key insights: Once-weekly injections improve patient compliance Oral options like Rybelsus are expanding accessibility Dual agonists (like tirzepatide) are pushing outcomes even further But its not just about benefits: Common adverse effects include nausea, vomiting, and GI discomforthighlighting the importance of dose titration and patient monitoring

Current evidence suggests that most cases of hair loss associated with GLP-1 medications are related to rapid weight loss, nutritional changes, and metabolic stress , rather than a direct drug effect

Which is better

1 Excess adiposity is a major contributor to BP elevation, with estimates suggesting that obesity causes 65%-78% of primary hypertension cases