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Suspender el medicamento y consultar de inmediato

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Excessive Bleeding: If the injection site bleeds for more than a minute or two after the needle is withdrawn, you should discuss this with your provider, as it may relate to other medications or underlying health conditions

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The fact that the double-cysteine mutations only partially abolish the physiological function may imply that not all the expressed mutants have an intact disulfide bridge and that the observed conformation is only one possible inactive state on the cell surface, as supported by the EM data and MD simulations below

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[DOI] [PMC free article] [PubMed] [Google Scholar] 3.Naslund E, Barkeling B, King N, et al

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