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However, there have been relatively few studies on the mechanism of GLP-1RAs in the treatment of chronic pain

A previous review of animal studies from the University of Amsterdam linked GLP-1 exposure during pregnancy to reduced foetal growth and skeletal abnormalities, and while human data is limited, the potential risks remain concerning

In 2021, semaglutide was approved by FDA for weight loss and quickly achieved commercial success

Some patients successfully transition from insulin to GLP-1 therapy , particularly if their Type 2 diabetes was caught relatively early
