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The SURPASS-2 trial showing tirzepatide achieving significantly greater HbA1c reduction and weight loss than semaglutide in T2DM patients, and the SURMOUNT trials showing up to 22% average body weight reduction in obese patients, have established tirzepatide as the clinical performance leader in the class

While clinical settings use DEXA scans for high precision, handheld devices utilizing bioelectrical impedance are becoming accessible for home use to determine shifts in tissue [2]

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Moreover, compounded drugs are not subject to the same rigorous clinical testing as their FDA-approved counterparts