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The efficacy of iGlarLixi in patients 65 years of age has been shown to be comparable with that of younger counterparts, and it can be used as an adjunct to diet and exercise in adults for the treatment of T2D that is inadequately controlled on oral glucose-lowering agents, GLP-1 RA, or basal insulin

Is the diminished incretin effect in type 2 diabetes just an epi-phenomenon of impaired beta-cell function

Reactive oxygen species can adversely affect many cellular structures and processes including nuclear DNA, mitochondrial dynamics and function, lipids, proteins, calcium homeostasis, cellular architecture, receptor trafficking and endocytosis, and energy homeostasis

When to seek medical care: Contact your healthcare provider promptly if you experience severe or persistent abdominal pain, pain that radiates to your back, persistent vomiting, inability to pass gas or stool, yellowing of skin/eyes, fever with abdominal symptoms, or signs of dehydration