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However, a recent cohort study observed a significant increase in depression, anxiety, and suicidal behavior associated with GLP-1 use

It seems likely that inter-organ communication, perhaps facilitated by neural pathways, contributes to the widespread anti-inflammatory actions of GLP-1 in tissues that do not contain GLP-1R+ immune cells [98]

[DOI] [PMC free article] [PubMed] [Google Scholar] 25.Gupta S., Sen U

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