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On a longer timeline of two years, some users have experienced pancreatitis, vision decline and gallbladder issues, though the cases are rare

4, the vast majority of the GLP-1 stimulatory activity was present in the greater than 100 kDa fraction of the bacterial supernatants (2507 1000 pM of GLP-1 for JA1, 1998 570 pM of GLP-1 for ATCC 12228 compared to 482 20 pM for the media control) with little activity remaining in the less than 100 kDa fractions (752 625 pM of GLP-1 for JA1, 545.3 363.5 pM of GLP-1 for ATCC 12228, compared to 487 182 pM for the media control) and no activity in the less than 3 kDa fraction (410 131 pM of GLP-1 for JA1, 347 85 pM of GLP-1 for ATCC 12228 compared to 482 20 pM for the media control)