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Sin embargo, dos estudios aleatorizados, doble ciego, que incluyeron 16.492 pacientes y 5.380 pacientes con DM2, el Saxagliptin Assessment of Vascular Outcomes Reported (SAVOR)70 y el Examitation of Cardiovascular Outcomes with Alogliptin versus standar of care (EXAMINE)71, reportaron tasas bajas de pancreatitis aguda similares a los grupos placebo (EXAMINE, 22 y 16 pacientes) y (SAVOR, 12 y 8 pacientes)

Individuals with a personal history of pancreatitis, gallstones, or elevated triglycerides require enhanced screening and may benefit from alternative weight loss approaches or closer monitoring protocols

Nenhum dos frmacos deve ser utilizado no tratamento da diabetes Diabetes Diabetes mellitus (DM) is a metabolic disease characterized by hyperglycemia and dysfunction of the regulation of glucose metabolism by insulin

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