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Moreover, expression of the pro-apoptotic protein Bax was reduced while Bcl2 expression increased, revealing that GLP-1RA can inhibit the apoptotic pathway

This study identified significant dose-response relationships for Cotadutide, Danuglipron, JNJ-64565111, Retatrutide, Orforglipron, and injectable Semaglutide (Equations Equation 1, Equation 2, Equation 3, Equation 4, Equation 5, Equation 6), with effective doses (doses achieving 50 % of the Emax value) of 0.219 mg, 80 mg, 6.73 mg, 4 mg, 14.6 mg, and 0.384 mg, respectively
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Wu Q, Li D, Huang C, et al
