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Acknowledgments The authors would like to recognize the contributions of Joy Gargis, Jose Guzman, Payton Kehn, Jennifer Nydell, Alexa Weimar and Karen Wong, who monitored the study, Jenna Encina and Nancy Torrence, who interacted with subjects at the study sites, John Shultz of Cetero Labs (Miami Gardens, FL, USA) and Don Tredway who advised on the manuscript

Its possible later trials wont replicate the promising results from the early stage trialthe majority of drugs fail during clinical testingor Novo may choose to focus its attention elsewhere

The SmPC advises that doses of these medications may need to be reduced when starting Wegovy

It is a demonstration model designed by the Centers for Medicare and Medicaid Services (CMS) to test whether structured GLP-1 access, combined with lifestyle interventions, can improve health outcomes while remaining fiscally sustainable