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FDA-approved semaglutide has undergone rigorous clinical trials to confirm its safety, efficacy, and consistent dosing, specifically for weight management
doi: 10.1017/S0033291708003723 67 GoldsmithD

Efficacy Estimand Change from Baseline HbA1c, source: Additionally, the 12 mg and 36 mg doses demonstrated clinically meaningful and statistically significant reductions in body weight compared to the placebo