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You can only get semaglutide legitimately through a prescription written by a licensed provider

If swallowed, tirzepatide would be destroyed by stomach acid and digestive enzymes

GLP-1 receptors are expressed on up to 70% cerebral arterioles [18] and endothelial cells, and experimental models demonstrate that GLP-1 signaling promotes arteriolar vasodilation, improved endothelial nitric oxide signaling, and angiogenic pathways such as VEGF upregulation, all of which enhance nutrient and oxygen delivery to metabolically active brain regions [13,14]

Compounded oral semaglutide is not FDA-approved as a branded medication, but it is manufactured by licensed 503A compounding pharmacies