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1,3 Most people tolerate GLP-1s better with a slow titration schedule, smaller and lower-fat meals, adequate hydration, and limiting alcohol or known trigger foods

Soluble fibre is particularly effective as gut bacteria ferment it into short-chain fatty acids that directly trigger GLP-1 release from intestinal L-cells

However, the current treatments for Alzheimer's disease are symptomatic and they target neurotransmission rather than neurodegeneration or neuronal metabolism [152]