how long has glp 1 been around The expanding landscape of GLP-1 medicines The History of GLP-1s
Description
On average, when a GLP-1 receptor agonist is added to diet and exercise for longer than six months, a lowering of HbA 1c by about 1% (11mmol/mol) has been demonstrated, along with weight loss of 1 to 3 kg

Lee MC, Tu YT, Lee CC, Tsai SC, Hsu HY, Tsai TY, et al
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Although not directly related to inflammation due to a physiologic change in the microenvironment, GLP-1RAs have the potential to replace current standard of care treatment for IIH and can ultimately contribute to improved patient outcomes in the field of neuro-ophthalmology