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Exercise, sleep, and nutrition remain indispensable for preserving metabolic health and preventing the chronic energy deficits that likely underlie dementia and Alzheimers disease

Data show that fasting reduces DBI expression in the subpostrema border and fourth ventricle region, but treatment with exendin-4 restored expression to fed-state levels

These medications work gradually, and people see the best results in coordination with lifestyle changes and a reduced-calorie diet

Practical guidance on the initiation, titration, and switching of basal insulins: a narrative review for primary care