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Description
Enhanced insulin sensitivity through GLP-1 and GIP pathways improves glucose uptake in muscle tissue, supporting muscle protein synthesis and reducing proteolysis

The weekly schedule differs from some other GLP-1 therapies and was specifically chosen in clinical trials because it provides optimal receptor activation without requiring daily administration

Eating large, irregular meals can blunt GLP-1 response

Results here will determine whether retatrutide pursues a combined obesity-and-diabetes indication
