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This is the specific gap NAD+ supplementation is meant to address

There was no increased rate of adverse effects leading to discontinuation of treatment in GLP-1RA users compared with nonGLP-1RA users (112)

Notably, these drugs are currently not covered for weight loss in Medicare, due to a long-time exclusion of treatment for weight loss

The numbers tell the story: patients on these medications have higher rates of retained gastric contents during esophagogastroduodenoscopy (EGD) compared to non-users 8.07% versus 3.49% [14]
