asa guidelines for glp 1 agonists The New Weight Management Meds How should we approach patients

The recent NEJM findings suggest GLP-1 pills can provide health improvements that are directly in line with what weve seen in the other injectable GLP-1 receptor agonists, says Matthew Cavender, a study co-author and a cardiologist at the University of North Carolina School of Medicine

Interestingly, this study did not detect the expression of AXIN2, FZD4, TCF4, WNT5A, WNT3, WNT4, or WNT7A genes in the ovaries of either PCOS patients or healthy women (57)

In a 64-week clinical trial , the Wegovy pill resulted in an average weight loss of 13.6%, and in a 68-week clinical trial, the Wegovy injection produced an average weight loss of 14.9%

Quick Answer: GLP-1 receptor agonists produce modest cholesterol reductions (LDL-C by 2-10%, triglycerides by 10-20%) but should complement, not replace, statin therapy for lipid management