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Description
It is suggested that melanin plays an important role by regulating anti-inflammatory related factors and signaling pathways

It does not directly increase energy expenditure

Shifts in hormones and metabolism may also contribute to breakouts, dryness, or other complexion changes

Clinical markers of enhanced fat oxidation in Retatrutide trials include reduced triglyceride levels (fewer circulating fats), improved liver fat content (enhanced hepatic fat oxidation), and maintained lean mass relative to fat mass loss (preferential fat oxidation versus protein catabolism)
