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Currently, there is no official pharmacological interaction documented between Ozempic and the major classes of antidepressants, including selective serotonin reuptake inhibitors (SSRIs), serotonin-noradrenaline reuptake inhibitors (SNRIs), tricyclic antidepressants (TCAs), or monoamine oxidase inhibitors (MAOIs)

Furthermore, an engineered therapeutic, AMG-133, has been developed, consisting of a GIP receptor-neutralizing antibody covalently linked to two GLP-1 receptor agonist peptide molecules [92]

Reduced calorie intake also helps with weight loss

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