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It is important to develop strategies to prevent or mitigate this phenomenon of weight regain, which may include a gradual reduction in the dose of SMG, participation in specific lifestyle programs after discontinuation of SMG, or the determination of criteria for new SMG treatment cycles in case of rapid weight regain [183]

Michael Weintraub, assistant clinical professor of endocrinology at NYU Langone in New York

Short-term users faced higher risks of each outcome compared to long-term users

Greater dose-ranging effects on A1C levels than on glucosuria with LX4211, a dual inhibitor of SGLT1 and SGLT2, in patients with type 2 diabetes on metformin monotherapy