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Description
Under conditions of low glucose, oxidative stress, or inflammation, mitochondria increase production of MOTS-C, which then: Enters the nucleus to modulate transcription of genes associated with antioxidant defenses, such as NRF2 targets

[,] Understanding the etiopathogenesis of obesity is complex

Overweight/Obese group: Out of 979 patients, 361 were on semaglutide, and 618 were on non-GLP-1 RA medications

Morton RW, et al