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Similarly, the LRP5 protein level was significantly reduced following the knockdown of LRP5 (Figures 5C, F, Supplementary Table S2)

Conclusion: This study provided a preliminary understanding of the GLP-1 signaling-related genes in pan-cancer, showing the prognosis significance and potential immunotherapeutic values in most cancer types, and verified the potential anticancer effect of GLP-1 receptor agonist in CRC

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