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This may pose challenges for healthcare organizations screening GLP-1RAs for introduction into their hospitals, particularly for those without the capacity to conduct drug evaluations independently

Orforglipron represents a potential paradigm shift as the first oral non-peptide GLP-1 agonist without fasting restrictions, and it demonstrated superiority over oral semaglutide in the head-to-head ACHIEVE-3 trial for both HbA1c and weight loss

Do not take more than 8 chewable tablets in 24 hours, or as directed by a doctor
