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Description
[86] found that semaglutide, as a GLP-1 analog, can directly act on fat cells, increase the expression of thermogenic genes for browning phenotype maintenance, improve the expression of UCP1, mitochondrial biosynthesis and thermogenic marker, thereby contributing to weight loss

Neither medication is recommended during breastfeeding due to limited safety data rather than confirmed harm

doi: 10.4103/0019-5545.69268

How Semaglutide Works for Lipedema Symptom Management Semaglutide activates GLP-1 receptors in the brain and digestive system, reducing appetite signals and promoting satiety
