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how long have semaglutides been studied Variable weight-loss and cardiovascular benefits were seen with GLP-1 drugs in a systematic review and network meta-analysis, but effects on quality of life were less clear. https://www.medpagetoday.com/primarycare/obesity/122142 In the original clinical trials
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Ipragliflozin add-on therapy to a GLP-1 receptor agonist in japanese patients with type 2 diabetes (AGATE): a 52-week open-label study
This leads to substantial, often rapid, weight loss observed in clinical studies
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