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These small molecule agonists increased insulin levels in primates but not rodents, which is explained by a cryo-EM structure that revealed a binding pocket requiring primate-specific tryptophan 33

Increased GLP2R expression in gastric chief cells of patients with severe obesity regardless of diabetes status

Lancet 402(10397):20334 Folkhlsomyndigheten (2023) Statistik om vervikt och fetma hos vuxna

While the early findings are exciting, these therapies should not be prescribed based on brain health claims alone
