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Factors to discuss Clinicians and patients should discuss benefits, harms, costs, weight-loss goals, access and availability, clinical comorbidities, life expectancy, values and preferences, and contraindications and warnings when initiating a recommended drug for weight loss or switching to another recommended treatment due to an inadequate response, Qaseem and colleagues wrote

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They also called for randomised trials with standardised erectile dysfunction assessments to further explore the association and investigate underlying biological pathways

In the United States, the monthly cost of GLP-1 medication can range from approximately $900 to over $1,300 without insurance coverage