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El ajuste post hoc para HbA1C y otros factores de riesgo renal tradicionales no tuvo una influencia importante en el beneficio renal con liraglutida, semaglutida o dulaglutida en los CVOT, ni hubo diferencias en el control glucmico en el estudio AWARD-766

Patients with diabetes should discuss their condition during the intake questionnaire and initial consultation to determine eligibility

Wharton S, Serodio KJ, Kuk JL, Sivapalan N, Craik A, Aarts M-A

These results suggested that GLP-1 expression was gradually decreased in CM, and also revealed that although the protein expression of GLP-1R was upregulated after NTG stimulation, the amount of GLP-1Rs that can be activated was decreased, so the activity of GLP-1R in the TNC in CM model was actually inhibited