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Table 3 Results of a 52-week Monotherapy Trial in Adults with Type 2 Diabetes Mellitus a Figure 3 Mean HbA 1c for Adult Patients with Type 2 Diabetes Mellitus who Completed the 52-week Trial and for the Last Observation Carried Forward (LOCF, intent-to-treat) data at Week 52 (Monotherapy) Combination Therapy Add-on to Metformin In this 26-week trial, 1,091 adult patients with type 2 diabetes mellitus were randomized to liraglutide injection 0.6 mg, liraglutide injection 1.2 mg, liraglutide injection 1.8 mg, placebo, or glimepiride 4 mg (one-half of the maximal approved dose in the United States), all as add-on to metformin

Both animal and human studies suggest that the most common gastric cellular defects in gastroparesis are the loss of expression of nNOS and the loss of ICC [4]

Henriette Svarre Nielsen von der Abteilung fr Gynkologie und Geburtshilfe am Universittsklinikum Hvidovre in Kopenhagen, Dnemark, die die Studie leitete, erklrte: Die Behandlung mit GLP-1-Rezeptoragonisten (GLP-1-RA) hat sich in den letzten Jahren weltweit zum Medikament mit dem strksten Anstieg an Verschreibungen entwickelt