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Always remember to perform a small patch test first

Barring that, consider: If your symptoms noticeably worsen in the hours or days after starting tirzepatide, its almost certainly due to the medication

Structurally, resmetirom (MGL-3196) is a synthetic, non-iodinated small molecule that selectively targets THR-

Contact your provider promptly if you experience severe or persistent gastrointestinal symptoms while using both medications, including: severe diarrhea lasting more than 24 hours, signs of dehydration (decreased urination, dizziness, extreme thirst, dry mouth), persistent vomiting preventing adequate fluid intake, severe abdominal pain or cramping, or blood in stool