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If this occurs, GLP-1 and GIP therapy should be withheld while this is investigated

NIH LactMed reports tirzepatide is usually undetectable in breast milk and unlikely to be absorbed by the infant, but FDA labeling still states that data are insufficient to assess infant risk. Because of this uncertainty, many clinicians recommend discontinuing tirzepatide when breastfeeding is planned

These medications are highly effective but come with a unique profile of adverse effects that affect multiple organ systems and present important considerations for emergency clinicians

Glucagon-like peptide 1 receptor agonists in type 1 diabetes mellitus