glp-1 secretion mechanism Frontiers GLP-1-based therapies for type 2
Description
On a cellular level, the polarization of macrophages has been stimulated by this molecule, shifting them from the inflammatory M1 phenotype to the anti-inflammatory M2 phenotype, which plays a vital role in tissue regeneration as well in reducing inflammation, as they produce cytokines like IL-10 and TGF-[5]
34 (1), 5974.e10
Systematic review of type 1 and type 2 diabetes mellitus and risk of fracture
as shown for both GLP1 receptor agonists and the antagonist LUXendin645 (Ast et al., 2020
