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Subgroup analyses based on baseline BMI categories showed inconsistent trends in the semaglutide arm: weight loss during treatment (week 0 to week 68) showed no clear trend across increasing BMI categories, but over week 0 to week 120 showed a trend for greater weight loss in the subgroups of patients with higher versus lower baseline BMI categories, in part owing to a lesser weight regain in the 40 kg/m 2 or higher subgroup than most others

5 At one time, it was theorized that there was a single hormone responsible for this activity, but it was discovered that two hormones secreted from the intestines are primarily responsible for the incretin effect, GLP-1 and glucose-dependent insulinotropic polypeptide (GIP)

Microdosing may help tackle all these problems as it involves smaller doses that bring subtle and sustainable results instead of rapid changes

Its rich profile of protein, healthy fats, and fiber makes it a powerful ally in supporting stable blood sugar and promoting satiety, which can complement Mounjaros effects beautifully