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However, its future trajectory is far from linear as many uncertainties remain, e.g., acceptance of obesity as a chronic disease, budget impact faced by payers and health systems willingness and ability to pay, the readout of further cardiovascular outcomes trials after the high profile results of 2023s SELECT trial for Wegovy, or new entrants challenging first generation therapies with alternative mechanisms of action (MoA) to address shortcomings such as gastrointestinal tolerability, current drugs being injectables, or the durability and quality of weight loss which distinguishes between fat and lean body mass

Muscle quality, insulin sensitivity, mitochondrial efficiency, intramuscular fat , may actually improve on GLP-1 therapy

Adding Dexcom G7 to your GLP-1 therapy leads to lower A1C than GLP-1 alone and helps you realize your goals faster

Its predominant action is on the postprandial glucose levels, with extraglycemic effects on fat metabolism and endovascular function